Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412039 | 0.90 | MAPT (0.72) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL19163369 | 0.87 | ALDH1A1 (0.68) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL6411001 | 0.85 | HTT (0.67) | KMT2AMEN1GAACYP3A4CYP2C9 | |
| SCHEMBL5338687 | 0.83 | MAPT (0.76) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15983619 | 0.83 | MEN1 (0.65) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL6404125 | 0.83 | GAA (0.71) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL15983434 | 0.83 | ALDH1A1 (0.77) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL18556583 | 0.82 | RECQL (0.62) | KMT2AMEN1GAACYP1A2CYP3A4 | |
| SCHEMBL5480773 | 0.82 | ALDH1A1 (0.78) | GAAALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL5711647 | 0.82 | ALDH1A1 (0.78) | GAAALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885MEN1 3562/4885GAA 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.