Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CDC25A | P30304 | 1/20 | 0.89 |
| ▸ | CDC25B | P30305 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ALPG | P10696 | 1/20 | 0.66 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147233 | 0.94 | CDC25A (1.00) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4205396 | 0.92 | ALDH1A1 (0.85) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL23527313 | 0.89 | ALDH1A1 (0.84) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4203731 | 0.88 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL18556537 | 0.87 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4209017 | 0.86 | POLB (0.80) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4200790 | 0.85 | ALDH1A1 (0.83) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4203026 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL23527195 | 0.84 | ALDH1A1 (0.77) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B | |
| SCHEMBL4206769 | 0.84 | CDC25A (0.75) | ALDH1A1MAPTL3MBTL1CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885MAPT 2111/4885L3MBTL1 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.