Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721911 | 1.00 | KMT2A (0.60) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL5722065 | 0.92 | KMT2A (0.63) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL5722072 | 0.92 | KMT2A (0.71) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL5721990 | 0.91 | KMT2A (0.60) | KMT2AMEN1RECQLMAPTNPC1 | |
| SCHEMBL6399978 | 0.90 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTERCC5 | |
| SCHEMBL6398727 | 0.90 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTERCC5 | |
| SCHEMBL6399149 | 0.89 | MEN1 (0.54) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL6399550 | 0.88 | KMT2A (0.78) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL6404282 | 0.87 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTPABPC1 | |
| SCHEMBL6400580 | 0.87 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | KMT2A 4040/4885MEN1 3721/4885RECQL 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.