Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410634 | 0.94 | CYP3A4 (0.61) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6407998 | 0.89 | TSHR (0.72) | TSHRALDH1A1L3MBTL1NPC1 | |
| SCHEMBL6405988 | 0.87 | ALDH1A1 (0.57) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6403838 | 0.87 | TSHR (0.65) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6403527 | 0.86 | TSHR (0.66) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6405743 | 0.86 | CYP3A4 (0.69) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL6405039 | 0.85 | TSHR (0.63) | TSHRALDH1A1L3MBTL1NPC1 | |
| SCHEMBL4234280 | 0.85 | TSHR (0.63) | TSHRALDH1A1L3MBTL1NPC1 | |
| SCHEMBL6407000 | 0.84 | TSHR (0.57) | TSHRALDH1A1CPB1 | |
| SCHEMBL6407843 | 0.83 | NPC1 (0.63) | TSHRALDH1A1CYP3A4CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TSHR 3470/4885ALDH1A1 720/4885CYP3A4 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.