Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948198 | 0.83 | SLC28A3 (0.42) | TYRSLC5A1TYMPSLC28A3CA12 | |
| SCHEMBL2962105 | 0.81 | SLC28A3 (0.47) | TYRSLC5A1TYMPSLC28A3 | |
| SCHEMBL14975385 | 0.72 | SLC5A2 (0.49) | TYRACHESLC5A2SLC5A1SLC28A3 | |
| SCHEMBL5032807 | 0.72 | SLC5A2 (0.49) | TYRACHESLC5A2SLC5A1SLC28A3 | |
| Curculigoside A SCHEMBL29419841 | 0.71 | SLC28A3 (0.55) | TYRACHESLC5A2SLC5A1TYMP | |
| SCHEMBL9014071 | 0.71 | CA12 (0.48) | TYRSLC5A2KDM4EPOLBGAA | |
| SCHEMBL9014307 | 0.71 | CA12 (0.48) | TYRSLC5A2KDM4EPOLBGAA | |
| SCHEMBL9014322 | 0.71 | CA12 (0.48) | TYRSLC5A2KDM4EPOLBGAA | |
| SCHEMBL9013970 | 0.71 | CA12 (0.48) | TYRSLC5A2KDM4EPOLBGAA | |
| SCHEMBL9014273 | 0.70 | SLC28A3 (0.50) | TYRSLC5A2SLC5A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939570-B1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON (US) | 2005-09-06 | — | — | US | disclosed |