Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 4/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962105 | 0.95 | SLC28A3 (0.47) | SLC28A3TYMPTYRSLC5A1ALDH1A1 | |
| Curculigoside A SCHEMBL29419841 | 0.89 | SLC28A3 (0.55) | SLC28A3TYMPTYRSLC5A1DYRK1A | |
| Curculigoside B SCHEMBL29419859 | 0.84 | SLC28A3 (0.60) | SLC28A3TYMPTYRSLC5A1DYRK1A | |
| Curculigoside B SCHEMBL7953777 | 0.84 | SLC28A3 (0.60) | SLC28A3TYMPTYRSLC5A1DYRK1A | |
| SCHEMBL6405014 | 0.83 | TYR (0.43) | SLC28A3TYMPTYRSLC5A1CA12 | |
| Salireposide SCHEMBL29891482 | 0.72 | TYMP (0.66) | SLC28A3TYMPTYRSLC5A1 | |
| SCHEMBL5032807 | 0.70 | SLC5A2 (0.49) | SLC28A3TYRSLC5A1 | |
| SCHEMBL14975385 | 0.70 | SLC5A2 (0.49) | SLC28A3TYRSLC5A1 | |
| SCHEMBL30637402 | 0.69 | TYMP (0.55) | TYMPTYRSLC5A1 | |
| SCHEMBL30637489 | 0.69 | TYMP (0.59) | SLC28A3TYMPTYRSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080206162-A1 | Composition and Methods for Treating Alzheimer's Disease and Other Amyloidoses | UNIVERSITY OF WASHINGTON | 2008-08-28 | — | — | US | claimed |
| EP-1019044-B1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2007-04-11 | — | — | EP | claimed |
| US-20040086585-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-06 | — | — | US | claimed |
| US-20040076698-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-22 | — | — | US | claimed |
| EP-1019044-A4 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2004-01-07 | — | — | EP | claimed |
| US-20010055630-A1 | Compostion and methods for treating alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-12-27 | — | — | US | claimed |
| EP-1019044-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | University of Washington (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1998051302-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 1998-11-19 | — | — | WO | claimed |
| US-7754250-B2 | Composition and methods for treating Alzheimer's disease and other amyloidoses | PROTEOTECH, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080206162-A1 | Composition and Methods for Treating Alzheimer's Disease and Other Amyloidoses | UNIVERSITY OF WASHINGTON | 2008-08-28 | — | — | US | disclosed |
| EP-1019044-B1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2007-04-11 | — | — | EP | disclosed |
| US-7029710-B2 | Methods of isolation of amyloid inhibitory ingredients within Uncaria tomentosa | UNIVERSITY OF WASHINGTON (US) | 2006-04-18 | — | — | US | disclosed |
| US-6939570-B1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON (US) | 2005-09-06 | — | — | US | disclosed |
| US-20040086585-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-06 | — | — | US | disclosed |
| US-20040076698-A1 | Composition and methods for treating Alzheimer's disease and other amyloidoses | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-22 | — | — | US | disclosed |
| EP-1019044-A4 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIV WASHINGTON (US) | 2004-01-07 | — | — | EP | disclosed |
| US-6346280-B1 | Composition and methods for inhibiting the formation of brain amyloid deposits | UNIVERSITY OF WASHINGTON | 2002-02-12 | — | — | US | disclosed |
| US-6264994-B1 | Compositions for treating alzheimer's disease and other amyloidoses | UNIVERSITY OF WASHINGTON | 2001-07-24 | — | — | US | disclosed |
| EP-1019044-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | University of Washington (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998051302-A1 | COMPOSITION AND METHODS FOR TREATING ALZHEIMER'S DISEASE AND OTHER AMYLOIDOSES | UNIVERSITY OF WASHINGTON (US) | 1998-11-19 | — | — | WO | disclosed |