Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.36 |
| ▸ | HCN1 | O60741 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405072 | 0.95 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4CA2TDP1 | |
| SCHEMBL6400043 | 0.84 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1CHRM2 | |
| SCHEMBL6400041 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL23159802 | 0.76 | PPARA (0.31) | — | |
| SCHEMBL6400218 | 0.75 | TSHR (0.46) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL6402078 | 0.75 | TSHR (0.46) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL8101650 | 0.73 | PPARA (0.30) | — | |
| SCHEMBL13325019 | 0.73 | MME (0.32) | TSHRCYP3A4TDP1CHRM2CHRM4 | |
| SCHEMBL6405723 | 0.73 | ALDH1A1 (0.45) | TSHRALDH1A1CYP3A4CA2TDP1 | |
| SCHEMBL304215 | 0.73 | SCN1A (0.52) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038283-A1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL, CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1227078-A1 | DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038283-A1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | SCO2, PDHX, DECR2 | TSHR 3173/4885ALDH1A1 3078/4885CYP3A4 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.