Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909971 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL6409632 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL4210924 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL6405333 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL15983445 | 0.74 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL19520381 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL4215408 | 0.73 | ALDH1A1 (0.72) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL4197472 | 0.73 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL4215437 | 0.73 | CYP2C19 (0.90) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL11510475 | 0.72 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | SMN1; SMN2 4793/4885ALDH1A1 720/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.