Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511705 | 0.88 | PARP1 (0.47) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27466112 | 0.84 | ALDH1A1 (0.35) | PARP1ALDH1A1MAPTTSHRGAA | |
| SCHEMBL997602 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL1004375 | 0.82 | ALDH1A1 (0.50) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5279852 | 0.81 | PARP1 (0.43) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL393948 | 0.81 | AKT1 (0.41) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27804306 | 0.80 | PARP1 (0.34) | PARP1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL30053495 | 0.80 | ALDH1A1 (0.48) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5189064 | 0.79 | ALDH1A1 (0.44) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5323674 | 0.79 | CYP3A4 (0.38) | KDM4EALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114025-A | Nematicidal cis (hetero)arylcyclopropylcarboxamide derivatives | SYNGENTA PARTICIPATIONS AG | 2014-10-22 | — | — | CN | disclosed |
| US-8294007-B2 | Membrane and 1,2-dipalmitoyl-sn-glycero-3-phospho-N-(2-hydroxymethyl)-3,5-divinylbenzamide; DNA sequencing | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2012-10-23 | — | — | US | disclosed |
| WO-2005084395-A2 | METHOD OF STABILIZATION OF FUNCTIONAL NANOSCALE PORES FOR DEVICE APPLICATIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050191616-A1 | Method of stabilization of functional nanoscale pores for device applications | THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY | 2005-09-01 | — | — | US | disclosed |