Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680413 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL6408696 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1SMN1; SMN2VCPMAPT | |
| SCHEMBL16592154 | 0.69 | MAOB (0.60) | ALDH1A1TDP1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL22623069 | 0.69 | NPC1 (0.58) | ALDH1A1TDP1TSHRKMT2APKM | |
| SCHEMBL6264446 | 0.69 | TSHR (0.64) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL6408255 | 0.68 | POLB (0.73) | ALDH1A1TDP1KMT2APKMRECQL | |
| SCHEMBL6403089 | 0.68 | USP2 (0.67) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL18618138 | 0.67 | MEN1 (0.58) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL22623196 | 0.67 | MAOB (0.53) | ALDH1A1TDP1KMT2AMEN1PKM | |
| SCHEMBL22593191 | 0.67 | ALDH1A1 (0.50) | ALDH1A1TDP1KMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885TDP1 288/4885TSHR 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.