Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6403257 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL6402568 | 0.96 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL6409020 | 0.96 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL6401687 | 0.96 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL6402583 | 0.83 | PTPN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6401847 | 0.82 | PTPN1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6400572 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6401668 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6402630 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6407262 | 0.79 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017729-B1 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND | BASELL POLYOLEFINE GMBH (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-6844288-B2 | Process for the preparation of ligands for metallogene catalysts | BASELL POLYOLEFINE GMBH (DE) | 2005-01-18 | — | — | US | disclosed |
| US-20030158356-A1 | Process for the preparation of substantially amorphous alpha-olefin polymers and compositions containing them and process for the preparation of bridged ligand | EQUISTAR CHEMICALS, LP | 2003-08-21 | — | — | US | disclosed |
| US-20020169260-A1 | Process for the preparation of ligands for metallocene catalysts | RESCONI LUIGI (IT) | 2002-11-14 | — | — | US | disclosed |
| US-6423796-B1 | COORDINATION CATALYST | BASEL TECHNOLOGY COMPANY BV (NL) | 2002-07-23 | — | — | US | disclosed |
| WO-2000001738-A9 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-07-27 | — | — | WO | disclosed |
| EP-1017729-A2 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND | Montell Technology Company bv (NL) | 2000-07-12 | — | — | EP | disclosed |
| WO-2000001738-A2 | PROCESS FOR THE PREPARATION OF SUBSTANTIALLY AMORPHOUS ALPHA-OLEFIN POLYMERS, COMPOSITIONS CONTAINING THEM AND PROCESS FOR THE PREPARATION OF BRIDGED LIGAND | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-01-13 | — | — | WO | disclosed |