SCHEMBL6405941

SCHEMBL6405941

Fc1cccc(C(F)Cl)c1F

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
BCHE P06276 1/20 0.37
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
GLS O94925 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16956757 0.80 CES2 (0.47) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL4219819 0.80 IDO1 (0.41) CES2CES1SLC6A2SLC6A4IDO1
SCHEMBL10779530 0.78 CES2 (0.42) CES2CES1
SCHEMBL29100191 0.76 CES2 (0.44) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL7777116 0.76 CES2 (0.53) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL1600457 0.76 CES2 (0.44) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL6824093 0.76 CES2 (0.44) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL29095954 0.76 CES2 (0.41) CES2CES1BCHESLC6A2SLC6A4
SCHEMBL16781678 0.76 CES2 (0.41) CES2CES1BCHEGLS
SCHEMBL4664137 0.74 CES2 (0.43) CES2CES1BCHEGLS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246762-A Preparation method of 2,4,5-trifluorophenylacetic acid 上海朴颐化学科技有限公司 2022-10-28 CN claimed
CN-220276949-U 2,4, 5-trifluoro benzyl chloride production system 宁夏华昊生物科技有限公司 2024-01-02 CN disclosed
CN-115246762-A Preparation method of 2,4,5-trifluorophenylacetic acid 上海朴颐化学科技有限公司 2022-10-28 CN disclosed
EP-1609774-A1 Fluorine atom containing benzyl ketone compound and process for producing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-12-28 EP disclosed
EP-0547557-B1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS (JP) 1994-07-27 EP disclosed
US-5310920-A N-vinylimidazolidine derivatives insecticides containing same as an effective ingredient MITSUI TOATSU CHEMICALS, INC. (JP) 1994-05-10 US disclosed
EP-0547557-A1 N-vinylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-06-23 EP disclosed