Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407794 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL6408648 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL6404349 | 0.84 | TSHR (0.67) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL6402385 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL6405138 | 0.81 | TSHR (0.63) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL4211195 | 0.75 | ALDH1A1 (0.62) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL28371584 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL6722154 | 0.73 | ALDH1A1 (0.64) | ALDH1A1TSHRPOLBHPGDLMNA | |
| SCHEMBL931766 | 0.73 | TSHR (0.53) | ALDH1A1TSHRNPSR1MEN1POLB | |
| SCHEMBL13905671 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TSHRNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885TSHR 3470/4885NPSR1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.