Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | TNK1 | Q13470 | 3/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6403678 | 0.89 | PARP1 (0.55) | PARP1KCNH2PARP2HTR6 | |
| Hydrochloric Acid SCHEMBL6406238 | 0.89 | PARP1 (0.76) | PARP1KCNH2PARP2DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6403697 | 0.85 | PARP1 (0.83) | PARP1KCNH2PARP2DRD2DRD4 | |
| SCHEMBL6405080 | 0.85 | PARP1 (0.56) | PARP1KCNH2PARP2TNK1TNK2 | |
| SCHEMBL6406134 | 0.82 | PARP1 (0.42) | PARP1KCNH2PARP2TNK1TNK2 | |
| SCHEMBL25821683 | 0.81 | PARP1 (0.69) | PARP1KCNH2PARP2TNK1 | |
| SCHEMBL6405680 | 0.80 | PARP1 (0.64) | PARP1KCNH2PARP2TNK1TNK2 | |
| SCHEMBL6556204 | 0.78 | PARP1 (0.53) | PARP1KCNH2PARP2TNK1TNK2 | |
| SCHEMBL6411435 | 0.77 | PARP1 (0.54) | PARP1 | |
| Hydrochloric Acid SCHEMBL6404123 | 0.76 | PARP1 (0.98) | PARP1KCNH2PARP2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171101-A1 | Phenanthridinones as parp inhibitors | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171101-A1 | Phenanthridinones as parp inhibitors | PARP1, PARP11, PARP2 | PARP1 1/4885KCNH2 2357/4885PARP2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.