Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 11/20 | 0.54 |
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404979 | 0.91 | PARP1 (0.56) | PARP1PPARGPPARASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6403678 | 0.79 | PARP1 (0.55) | PARP1SIGMAR1 | |
| SCHEMBL6406366 | 0.77 | PARP1 (0.62) | PARP1 | |
| SCHEMBL6406361 | 0.74 | PARP1 (0.59) | PARP1 | |
| SCHEMBL6405272 | 0.70 | PARP1 (0.85) | PARP1SIGMAR1 | |
| SCHEMBL2366274 | 0.70 | PARP1 (1.00) | PARP1 | |
| Hydrochloric Acid SCHEMBL2366728 | 0.69 | PARP1 (0.98) | PARP1 | |
| SCHEMBL6405080 | 0.69 | PARP1 (0.56) | PARP1 | |
| SCHEMBL6406134 | 0.69 | PARP1 (0.42) | PARP1 | |
| SCHEMBL11341093 | 0.68 | MAOB (0.53) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171101-A1 | Phenanthridinones as parp inhibitors | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171101-A1 | Phenanthridinones as parp inhibitors | PARP1, PARP11, PARP2 | PARP1 1/4885PPARG 3980/4885PPARA 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.