Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014818 | 0.85 | SMN1; SMN2 (0.68) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL11019180 | 0.75 | SMN1; SMN2 (0.58) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL11121930 | 0.75 | SMN1; SMN2 (0.73) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL11108446 | 0.74 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL29888697 | 0.74 | SMN1; SMN2 (0.71) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL10866421 | 0.74 | SMN1; SMN2 (0.59) | LMNAMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL20540763 | 0.73 | LMNA (0.65) | LMNAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10872581 | 0.72 | POLB (0.70) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL10894311 | 0.72 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL8972735 | 0.72 | SMN1; SMN2 (0.72) | LMNAMAPTSMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919389-B2 | Polymer compositions containing benzimidazole based stabilizer compounds | CROMPTON CORPORATION (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040180995-A1 | Polymer compositions containing benzimidazole based stabilizer compounds | ADDIVANT USA, LLC | 2004-09-16 | — | — | US | disclosed |