SCHEMBL6406590

SCHEMBL6406590

Cc1ccc(C(Br)CN)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
CHRNA7 P36544 1/20 0.39
ACHE P22303 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.36
HTR2A P28223 1/20 0.34
ALOX5 P09917 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 1/20 0.33
CA7 P43166 1/20 0.33
AGXT P21549 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972988 0.78 CHRNA7 (0.41) CHRNA7ACHETDP1ALDH1A1ALOX5
SCHEMBL953630 0.78 CHRNA7 (0.41) CYP1A2CHRNA7ACHETDP1ALDH1A1
SCHEMBL29239958 0.76 TAAR1 (0.58) TAAR1CYP1A2TDP1ALDH1A1
SCHEMBL28493299 0.76 CHRNA7 (0.39) CYP1A2CHRNA7ACHETDP1ALDH1A1
SCHEMBL25735106 0.76 CHRNA7 (0.39) CHRNA7ACHETDP1ALDH1A1CA7
SCHEMBL1976304 0.75 TAAR1 (0.59) TAAR1CYP1A2HTR2A
SCHEMBL3667006 0.75 CYP1A2 (0.42) TAAR1CYP1A2CYP2A6CHRNA7ACHE
SCHEMBL516439 0.75 TAAR1 (0.59) TAAR1CYP1A2CYP2A6CHRNA7ACHE
SCHEMBL9789948 0.74 CHRNA7 (0.38) CYP1A2CHRNA7ACHETDP1ALDH1A1
SCHEMBL8011990 0.74 TAAR1 (0.65) TAAR1CYP1A2CYP2A6CHRNA7ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed