Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406947 | 1.00 | TACR1 (0.57) | TACR1KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6406184 | 0.82 | TACR1 (0.62) | TACR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6406187 | 0.82 | TACR1 (0.62) | TACR1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6408869 | 0.79 | TACR1 (0.85) | TACR1 | |
| SCHEMBL5691094 | 0.77 | KDM4E (0.81) | KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5691088 | 0.77 | KDM4E (0.81) | KDM4ESMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8628619 | 0.76 | KDM4E (0.79) | KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6407058 | 0.75 | TACR1 (0.83) | TACR1 | |
| SCHEMBL6411916 | 0.75 | TACR1 (0.76) | TACR1 | |
| SCHEMBL6409801 | 0.74 | TACR1 (0.96) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038072-A1 | Nitrogeneous cyclic ketone derivative, process for producing the same, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2005-02-17 | — | — | US | disclosed |
| EP-1460062-A1 | NITROGENOUS CYCLIC KETONE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Chemical Industries, Ltd. (JP) | 2004-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038072-A1 | Nitrogeneous cyclic ketone derivative, process for producing the same, and use | BDKRB1, BDKRB2, TACR1 | TACR1 3/4885KDM4E 2064/4885SMN1; SMN2 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.