Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37854 | 0.96 | — | — | |
| SCHEMBL129166 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL77259 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL1609996 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL55416 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL451731 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL1610728 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL1611286 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL1612921 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL371663 | 0.92 | TSHR (0.61) | TSHRTHRBLMNASLC22A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261371-A1 | Pentanoic acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261371-A1 | Pentanoic acid derivatives | FFAR3, FFAR1, HCAR3 | TSHR 65/4885THRB 421/4885LMNA 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.