Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205338 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL10265071 | 0.86 | PRMT1 (0.56) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL1024927 | 0.85 | MAPT (0.66) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL29349570 | 0.85 | MAPT (0.66) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL13388766 | 0.85 | MAPT (0.62) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL16181494 | 0.85 | MAPT (0.53) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL13953177 | 0.85 | MAPT (0.53) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL621683 | 0.84 | CYP3A4 (0.51) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL14005748 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL620637 | 0.82 | CYP3A4 (0.51) | MAPTMEN1KMT2ATDP1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537853-A1 | Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers | L'OREAL (FR) | 2005-06-08 | — | — | EP | claimed |
| US-9745487-B2 | Yellow thermochromic dyes, inks composition and level indicators | CHROMATIC TECHNOLOGIES, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745487-B2 | Yellow thermochromic dyes, inks composition and level indicators | CHROMATIC TECHNOLOGIES, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| EP-3017010-B1 | YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS | CHROMATIC TECH INC (US) | 2017-05-17 | — | — | EP | disclosed |
| US-20170073359-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | MOLECULAR PROBES, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20160333210-A1 | Yellow Thermochromic Dyes, Inks Composition And Level Indicators | CHROMATIC TECHNOLOGIES, INC. (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160333210-A1 | Yellow Thermochromic Dyes, Inks Composition And Level Indicators | CHROMATIC TECHNOLOGIES, INC. (US) | 2016-11-17 | — | — | US | disclosed |
| US-9399716-B2 | Yellow thermochromic dyes, inks composition and level indicators | CHROMATIC TECHNOLOGIES INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-9399716-B2 | Yellow thermochromic dyes, inks composition and level indicators | CHROMATIC TECHNOLOGIES INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-20160139135-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | LIFE TECHNOLOGIES CORP (US) | 2016-05-19 | — | — | US | disclosed |
| WO-2015003046-A1 | YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS | CHROMATIC TECHNOLOGIES INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| US-8865891-B2 | Optically-detectable enzyme substrates and their method of use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| EP-1537853-A1 | Use of a composition comprising a compound comprising a lacton ring and/or a corresponding coloring agent with an open ring for dyeing keratinuous fibers | L'OREAL (FR) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160139135-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | MGAM, LCT, GAA | MAPT 2586/4885MEN1 3638/4885KMT2A 3746/4885 |
| US-20170073359-A1 | Optically-Detectable Enzyme Substrates and Their Method of Use | MGAM, LCT, GAA | MAPT 2586/4885MEN1 3638/4885KMT2A 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.