⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764019 | 1.00 | — | — | |
| SCHEMBL27736676 | 0.88 | — | — | |
| SCHEMBL8430113 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL6035330 | 0.81 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL16074967 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL16074722 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL16074879 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL16074770 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL16074900 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL16074838 | 0.79 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245596-A1 | Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin k inhibitors for the treatment of bone loss | SMITHKLINE BEECHAM CORPORATION | 2005-11-03 | — | — | US | disclosed |