SCHEMBL6407519

SCHEMBL6407519

O=C(N=CCc1ccccc1)N=CCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.46
ALDH1A1 P00352 2/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
AKR1B1 P15121 1/20 0.43
TOP1 P11387 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ARG2 P78540 1/20 0.41
KEAP1 Q14145 1/20 0.40
CTBP2 P56545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC3 O15379 1/20 0.38
MAPK1 P28482 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6662915 0.83 ALDH1A1 (0.45) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL10792863 0.83 IDO1 (0.44) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL29101742 0.82 ALDH1A1 (0.48) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL5665711 0.75 MAOB (0.59) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL265957 0.75 MAOB (0.59) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL1060278 0.75 MAOB (0.59) MAOBALDH1A1CES2CES1AKR1B1
SCHEMBL25271061 0.74 MAOB (0.57) MAOBALDH1A1CA1CA2ARG2
SCHEMBL4037964 0.74 MAOB (0.57) MAOBALDH1A1CA1CA2ARG2
SCHEMBL7951084 0.74 PTGDR2 (0.37) MAOBALDH1A1TOP1CA1CA2
SCHEMBL13716906 0.74 MAOB (0.41) MAOBALDH1A1CA1CA2ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110878035-A Method for preparing symmetrical urea compound 中国科学院化学研究所 2020-03-13 CN disclosed
US-20050222317-A1 Rubber composition THE YOKOHAMA RUBBER CO., LTD. 2005-10-06 US disclosed
EP-1443077-A2 Rubber composition containing carbon black THE YOKOHAMA RUBBER CO., LTD. (JP) 2004-08-04 EP disclosed
US-20030114577-A1 Rubber composition YOKOHAMA RUBBER CO., LTD., THE (JP) 2003-06-19 US disclosed
US-6200718-B1 A POLYMERIZED TONER OF CORE-SHELL STRUCTURE, COMPRISING CORE PARTICLES COMPOSED OF COLORED POLYMER PARTICLES WHICH CONTAIN A COMPOUND HAVING >C=N+ STRUCTURE IN ITS MOLECULE AND A COLORANT AND A LAYER OF POLYMER COVERING CORE PARTICLES NIPPON ZEON CO., LTD. (JP) 2001-03-13 US disclosed
EP-0947888-A1 POLYMER TONER AND METHOD OF PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1999-10-06 EP disclosed
US-5962575-A KNEADING; CONTROLLING CONCENTRATION THE YOKOHAMA RUBBER CO., LTD. (JP) 1999-10-05 US disclosed
EP-0831124-A1 CARBON BLACK FILLED RUBBER COMPOSITIONS THE YOKOHAMA RUBBER CO., LTD. (JP) 1998-03-25 EP disclosed
EP-0438248-B1 Preparation process of toner NIPPON ZEON CO (JP) 1996-07-24 EP disclosed
EP-0435544-B1 Abrasion-resistant rubber compositions NIPPON ZEON CO (JP) 1995-09-06 EP disclosed
US-5219942-A Blend of end-modified styrene-butadiene copolymer and diene rubber NIPPON ZEON CO., LTD. (JP) 1993-06-15 US disclosed
US-5217839-A Dispersion containing mixture of a polymer with a carbon nitrogen double bond and a colorant in a vinyl monomer NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5218023-A Anionic polymers NIPPON ZEON CO., LTD. (JP) 1993-06-08 US disclosed
US-5216080-A Butadiene-styrene copolymers endcapped with N-modified amino ketones, thioamino ketones, thioamino aldehydes, lactams, thiolactams, ethyleneurea and thioethylene urea; wear resistant, large-sized tires NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
US-5155161-A Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis NIPPON ZEON CO., LTD. (JP) 1992-10-13 US disclosed
EP-0488346-A1 Process for preparation of styrene resin composition and styrene resin composition NIPPON ZEON CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0438248-A2 Preparation process of toner NIPPON ZEON CO., LTD. (JP) 1991-07-24 EP disclosed
EP-0435544-A2 Abrasion-resistant rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0434353-A2 Rubber compositions NIPPON ZEON CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0382205-A2 Additive for thermosetting resins and thermosetting resin composition containing additive NIPPON ZEON CO., LTD. (JP) 1990-08-16 EP disclosed