Dimethylamine

Dimethylamine

SCHEMBL6407576

CC1=CC(=C(C#N)C#N)C=C(C=Cc2ccccc2)O1.CNC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
GLA P06280 2/20 0.35
GAA P10253 2/20 0.35
RAB9A P51151 2/20 0.35
ATM Q13315 2/20 0.35
TTR P02766 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HDAC6 Q9UBN7 1/20 0.32
CTSC P53634 1/20 0.32
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
MCL1 Q07820 1/20 0.31
KMT2A Q03164 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13354269 0.96 TTR (0.35) KDM4EALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL18721504 0.86 MCL1 (0.40) KDM4EALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL28789994 0.86 MCL1 (0.40) KDM4EALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL7600835 0.86 APP (0.42)
SCHEMBL7600829 0.86 APP (0.42)
SCHEMBL5448210 0.85 RELA (0.34) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL5448209 0.85 RELA (0.34) KDM4EALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL30619970 0.84 MEN1 (0.36) KDM4EALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL12175796 0.84 MEN1 (0.36) KDM4EALDH1A1HPGDMAPTSMN1; SMN2
SCHEMBL6741390 0.83 APP (0.37) KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1669191-A Laser gain medium for solid state dye laser BASF AG (DE) 2005-09-14 CN disclosed
US-6869696-B2 Organic red electro-luminescent device including a heterocyclic emitter SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2005-03-22 US disclosed
US-20030232215-A1 Organic Red Electro-Luminescent Device and Dopant SYNTEC GESELLSCHAFT FUER CHEMIE UND TECHNOLOGIE DER INFORMATIONSAUFZEICHNUNG MBH (DE) 2003-12-18 US disclosed
US-20030228486-A1 Organic Red Electro-Luminescent Device Including A Hetrocyclic Emitter SYNTEC GESELLSCHAFT FUER CHEMIE UND TECHNOLOGIE DER INFORMATIONSAUFZEICHNUNG MBH (DE) 2003-12-11 US disclosed