Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223856 | 0.87 | PGR (0.49) | PGRARNR3C1NR3C2 | |
| SCHEMBL1222351 | 0.82 | PGR (0.54) | PGRARNR3C1NR3C2 | |
| SCHEMBL6815705 | 0.79 | PGR (0.48) | PGRARNR3C1NR3C2 | |
| SCHEMBL1223203 | 0.73 | PGR (0.66) | PGRARNR3C1NR3C2 | |
| SCHEMBL1223858 | 0.71 | PGR (0.46) | PGRARNR3C1NR3C2 | |
| SCHEMBL4159226 | 0.71 | PGR (0.50) | PGRARNR3C1NR3C2 | |
| SCHEMBL6812414 | 0.71 | PGR (0.47) | PGRARNR3C1NR3C2 | |
| SCHEMBL7694585 | 0.70 | PGR (0.70) | PGRARNR3C1NR3C2 | |
| SCHEMBL1222388 | 0.69 | PGR (0.63) | PGRARNR3C1NR3C2 | |
| SCHEMBL1223621 | 0.69 | PGR (0.61) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173433-B1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | WYETH CORP (US) | 2005-12-28 | — | — | EP | claimed |