SCHEMBL6407837

SCHEMBL6407837

[CH2]C(O)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1876120 0.70
SCHEMBL8900657 0.70
SCHEMBL28853742 0.67
SCHEMBL3075465 0.67
SCHEMBL14754453 0.67
SCHEMBL790312 0.67
SCHEMBL214411 0.67
SCHEMBL16104649 0.67
SCHEMBL9064109 0.67
SCHEMBL27545572 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358132-B Abuse resistant capsules R.P.谢勒技术有限公司 2019-10-15 CN claimed
CN-101605794-B Azabenzofuranyl compounds and methods of use GENENTECH INC US 2013-06-12 CN claimed
CN-101842361-B Pyrazinone derivatives and their use in the treatment of lung diseases ASTRAZENECA AB 2013-06-05 CN claimed
CN-101679395-B Triazolyl aminopyrimidine compounds LILLY CO ELI 2012-06-13 CN claimed
CN-101679396-B Triazolylaminopyrimidine compounds LILLY CO ELI 2012-06-06 CN claimed
CN-101679396-A Triazolylaminopyrimidine compounds LILLY CO ELI 2010-03-24 CN claimed
CN-101679395-A triazolyl aminopyrimidine compounds LILLY CO ELI 2010-03-24 CN claimed
CN-101466725-A Amino derivatives of androstanes and androstenes as medicaments for cardiovascular disorders SIGMA TAU IND FARMACEUTI (IT) 2009-06-24 CN claimed
CN-101415679-A Water-soluble CC-1065 analogs and conjugates thereof SINTAGAR B V (NL) 2009-04-22 CN claimed
CN-101304978-A Quinazoline derivatives as multiplex inhibitors and process for their preparation HANMI PHARM IND CO LTD (KR) 2008-11-12 CN claimed
CN-101124199-A 5-substituted-2-phenylamino-benzamides as MEK inhibiting substances CHUGAI PHARMACEUTICAL CO LTD (JP) 2008-02-13 CN claimed
CN-101052620-A Benzamide compound ASTRAZENECA AB (SE) 2007-10-10 CN claimed
CN-1319092-A Benzamide derivatives and their use as cytokine inhibitors ASTRAZENECA AB (SE) 2001-10-24 CN claimed
CN-115616216-A Use of an agent that inhibits or blocks the interaction between FAAH and NLRP3 华南理工大学 2023-01-17 CN disclosed
CN-105358132-B Abuse resistant capsules R.P.谢勒技术有限公司 2019-10-15 CN disclosed
CN-105209457-A Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE DEUTSCHLAND 2015-12-30 CN disclosed
US-5496844-A Indole derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1996-03-05 US disclosed
EP-0639567-A1 INDOLE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1995-02-22 EP disclosed
CN-1094043-A Quinazoline derivant ZENECA LTD (GB) 1994-10-26 CN disclosed
CN-1046903-A Process for preparing heterocyclic ether derivatives ICI PLC (GB) 1990-11-14 CN disclosed