SCHEMBL790312

SCHEMBL790312

[CH2]C(NC)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8900657 0.74
SCHEMBL214411 0.70
SCHEMBL9064109 0.70
SCHEMBL28853742 0.70
SCHEMBL4078688 0.69
SCHEMBL6407837 0.67
SCHEMBL28104075 0.67
SCHEMBL28164403 0.67
SCHEMBL11289814 0.67
SCHEMBL11419119 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708321-B2 Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4 MERCK PATENT GMBH (DE) 2017-07-18 US claimed
CN-103717602-B Kinase inhibitors 加利福尼亚大学董事会 2016-11-09 CN claimed
US-20150361079-A1 Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 MERCK PATENT GMBH (DE) 2015-12-17 US claimed
EP-2951179-A1 SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS Merck Patent GmbH (DE) 2015-12-09 EP claimed
US-20140323464-A1 KINASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2014-10-30 US claimed
WO-2014117920-A1 SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS MERCK PATENT GMBH (DE) 2014-08-07 WO claimed
CN-103717602-A Kinase inhibitors UNIV CALIFORNIA 2014-04-09 CN claimed
EP-2710007-A2 KINASE INHIBITORS The Regents of the University of California (US) 2014-03-26 EP claimed
WO-2012158843-A2 KINASE INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 WO claimed
JP-2002521375-A 2002-07-16 JP claimed
EP-1133484-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS AstraZeneca AB (SE) 2001-09-19 EP claimed
WO-2000005223-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS ASTRAZENECA AB (SE) 2000-02-03 WO claimed
US-5580865-A ELASTASE INHIBITORS; ANTIINFLAMMATORY AGENTS; DEGENERATIVE DISEASES; EMPHYSEMA, ADULT RESPIRATORY DISTRESS SYNDROME, RHEUMATIC FEVER, SPONDYLITIS, GOUT, LUPUS AND PSORIASIS FARMITALIA CARLO ERBA S.R.L. (IT) 1996-12-03 US claimed
EP-0564835-A2 2,2-Disubstituted cephem sulphones PHARMACIA S.p.A. (IT) 1993-10-13 EP claimed
EP-4398038-A1 RECYCLING TREATMENT DEVICE, WASHING-OUT DEVICE, AND METHOD FOR MANUFACTURING FLEXOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2024-07-10 EP disclosed
US-20240210834-A1 WASHOUT PROCESSOR AND WASHING METHOD FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed
US-20240190726-A1 REGENERATION TREATMENT APPARATUS, WASHOUT PROCESSOR, AND MANUFACTURING METHOD OF FLEXOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2024-06-13 US disclosed
US-4148788-A Synthesis of thymosin α1 HOFFMANN-LA ROCHE INC. (US) 1979-04-10 US disclosed
US-4116951-A [Asn2 ]-thymosin α1 and analogs thereof HOFFMANN-LA ROCHE INC. (US) 1978-09-26 US disclosed
US-4105652-A Synthesis of human β-endorphin HOFFMANN-LA ROCHE INC. (US) 1978-08-08 US disclosed