Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170719 | 0.90 | NR4A2 (0.71) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL9812484 | 0.84 | NR4A2 (0.69) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL3618405 | 0.83 | MAPT (0.70) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL11849613 | 0.81 | NR4A2 (0.66) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL11093923 | 0.81 | MAOB (0.69) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL13483791 | 0.81 | MAOB (0.64) | NR4A2MAOBMAOAMAPTTP53 | |
| SCHEMBL6333131 | 0.79 | SMN1; SMN2 (0.62) | NR4A2MAOBMAOAMEN1KMT2A | |
| SCHEMBL6331482 | 0.79 | NR4A2 (0.48) | NR4A2MAOBMAOAMAPTMEN1 | |
| SCHEMBL6326819 | 0.79 | NR4A2 (0.63) | NR4A2MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL29001619 | 0.78 | SMN1; SMN2 (0.66) | NR4A2MAOBMAOAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841661-B2 | Glycopeptide antibacterial compounds, compositions containing same and methods of using same | PRINCETON UNIVERISITY (US) | 2005-01-11 | — | — | US | disclosed |
| US-6498238-B1 | Glycopeptide antibacterial compounds, compositions containing same and methods of using same | PRINCETON UNIVERSITY | 2002-12-24 | — | — | US | disclosed |