SCHEMBL3618405

SCHEMBL3618405

Oc1ccc(OCc2ccccc2Cl)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.70
GAA P10253 2/20 0.70
TP53 P04637 1/20 0.70
NR4A2 P43354 2/20 0.68
MAOB P27338 5/20 0.66
MAOA P21397 1/20 0.66
THRB P10828 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HTT P42858 1/20 0.56
RAD52 P43351 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
LMNA P02545 2/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
PTGS2 P35354 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HIF1A Q16665 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7170719 0.92 NR4A2 (0.71) MAPTGAATP53NR4A2MAOB
SCHEMBL9812484 0.86 NR4A2 (0.69) MAPTGAATP53NR4A2MAOB
SCHEMBL10897051 0.86 LMNA (0.65) MAPTGAATP53NR4A2MAOB
SCHEMBL6408450 0.83 NR4A2 (0.61) MAPTGAATP53NR4A2MAOB
SCHEMBL13483791 0.83 MAOB (0.64) MAPTGAATP53NR4A2MAOB
SCHEMBL11093923 0.83 MAOB (0.69) MAPTGAATP53NR4A2MAOB
SCHEMBL21762 0.83 NR4A2 (0.66) MAPTGAATP53NR4A2MAOB
SCHEMBL11849613 0.83 NR4A2 (0.66) MAPTGAATP53NR4A2MAOB
SCHEMBL2556153 0.82 NR4A2 (0.60) MAPTGAATP53NR4A2MAOB
SCHEMBL29954245 0.82 NR4A2 (0.60) MAPTGAATP53NR4A2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2036878-B1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-22 EP disclosed
US-7745669-B2 Process for production of alcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-29 US disclosed
US-20090259074-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-15 US disclosed
EP-2036878-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2009-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090259074-A1 PROCESS FOR PRODUCTION OF ALCOHOL COMPOUND XDH, ADH5, ADH1A MAPT 3916/4885GAA 1756/4885TP53 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.