SCHEMBL640850

SCHEMBL640850

CCCCCCC(C)P(=O)(O)C(C)CCCCCC.[Ni]

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.57
LAP3 P28838 2/20 0.53
SMPD1 P17405 3/20 0.52
S1PR2 O95136 5/20 0.48
S1PR1 P21453 5/20 0.48
S1PR3 Q99500 5/20 0.48
S1PR4 O95977 4/20 0.48
LPAR3 Q9UBY5 3/20 0.46
LPAR2 Q9HBW0 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329817 0.98 FDPS (0.59) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL28371605 0.98 FDPS (0.59) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL672807 0.96 FDPS (0.57) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL672708 0.96 FDPS (0.57) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL156200 0.96 FDPS (0.57) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL31556159 0.88 FDPS (0.53) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL2701638 0.87 FDPS (0.63) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL31556146 0.86 FDPS (0.52) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL7820207 0.84 FDPS (0.65) FDPSLAP3SMPD1S1PR2S1PR1
SCHEMBL7818091 0.84 FDPS (0.65) FDPSLAP3SMPD1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
US-20230144912-A1 METAL-BASED CATALYST FOR PRODUCING POLYDIENES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-05-11 US disclosed
US-20220213300-A1 Modified High-Cis Polybutadiene Polymer, Related Methods And Tire Components BRIDGESTONE CORPORATION (JP) 2022-07-07 US disclosed
US-20220144974-A1 Modified High-Cis Polybutadiene Polymer, Related Methods And Rubber Compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2022-05-12 US disclosed
US-20120255661-A1 PROCESSES FOR PREPARATION OF CYCLIC AND ACYCLIC DIENE COPOLYMER AND RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2012-10-11 US disclosed
US-20120108755-A1 BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE BRIDGESTONE CORPORATION (JP) 2012-05-03 US disclosed
US-8119736-B2 Branched polymers and methods for their synthesis and use BRIDGESTONE CORPORATION (JP) 2012-02-21 US disclosed
US-20100137520-A1 Branched Polymers and Methods for Their Synthesis and Use BRIDGESTONE CORPORATION (JP) 2010-06-03 US disclosed
US-7585805-B2 polymerization catalyst containing e.g.a combination or reaction product of triisobutylaluminum an alkylating agent, Ni(II) neodecanoate borate as nickel compound, trifluoride/n-hexanol complex as F2 compound and tin tetrachloride as Cl2 compound to polymerize 1,3-butadiene to cis-1,4-polybutadiene BRIDGESTONE CORPORATION 2009-09-08 US disclosed
US-20080255327-A1 addition polymerization of conjugated polyene monomer in the presence of polymerization catalysts comprising a mixture of a nickel-containing compound, an alkylating agent, a fluorine-containing compound, a carboxylic acid and an alcohol; controlling gelation, branching and molecular weight; efficiency BRIDGESTONE CORPORATION (JP) 2008-10-16 US disclosed
US-20070117942-A1 Nickel-based catalyst composition BRIDGESTONE CORPORATION 2007-05-24 US disclosed
EP-1788003-A1 Nickel-based catalyst composition Bridgestone Corporation (JP) 2007-05-23 EP disclosed
US-6699813-B2 COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS BRIDGESTONE CORPORATION (JP) 2004-03-02 US disclosed
US-20030176276-A1 Lanthanide-based catalyst composition for the manufacture of polydienes BRIDGESTONE CORPORATION (JP) 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB FDPS 2466/4885LAP3 4107/4885SMPD1 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.