Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969997 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL1970023 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| Bromide SCHEMBL28851069 | 0.84 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28245775 | 0.84 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL2484461 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL9735269 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL11673762 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL5617 | 0.79 | — | — | |
| SCHEMBL8373239 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| SCHEMBL13667433 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| US-6930111-B2 | Substituted heterocyclic compounds | CV THERAPEUTICS, INC. (US) | 2005-08-16 | — | — | US | disclosed |