Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336949 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL20547944 | 0.74 | HTT (0.66) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL6409632 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1ALOX15NPSR1CYP3A4MEN1 | |
| SCHEMBL6403551 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL5334498 | 0.71 | ALDH1A1 (0.45) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL1816886 | 0.70 | AVPR1A (0.49) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL6404745 | 0.68 | MAPK1 (0.68) | ALDH1A1HTTHSD17B10NPSR1MEN1 | |
| SCHEMBL11511734 | 0.68 | ALDH1A1 (0.57) | ALDH1A1HTTALOX15HSD17B10L3MBTL1 | |
| SCHEMBL6404149 | 0.68 | ALDH1A1 (0.64) | ALDH1A1HTTALOX15HSD17B10NPSR1 | |
| SCHEMBL6405016 | 0.68 | MAPK1 (1.00) | ALDH1A1HTTHSD17B10NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885HTT 2113/4885ALOX15 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.