Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409392 | 1.00 | GABRR1 (0.46) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL4746646 | 1.00 | GABRR1 (0.46) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL24035538 | 0.89 | GABRR1 (0.42) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL7715570 | 0.87 | KDM4E (0.40) | GABRR1ALOX15KDM4EALDH1A1LMNA | |
| SCHEMBL7715567 | 0.87 | KDM4E (0.40) | GABRR1ALOX15KDM4EALDH1A1LMNA | |
| SCHEMBL6542917 | 0.84 | CYP2C19 (0.50) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL19902117 | 0.84 | CYP2C19 (0.50) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL5349667 | 0.84 | CYP2C19 (0.50) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL23366184 | 0.84 | CYP2C19 (0.50) | GABRR1CYP2C19CYP1A2ALOX15KDM4E | |
| SCHEMBL375124 | 0.84 | CYP2C19 (0.50) | GABRR1CYP2C19CYP1A2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | ELAN PHARMACEUTICALS, INC. | 2005-08-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | BACE1, APP, BACE2 | GABRR1 1441/4885CYP2C19 4626/4885CYP1A2 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.