SCHEMBL7715570

SCHEMBL7715570

NC(=O)C1C[C@H](C(N)=O)C[C@H](C(N)=O)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
CYP2D6 P10635 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.33
GAA P10253 1/20 0.33
GABRR1 P24046 1/20 0.33
EPHX1 P07099 2/20 0.32
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715567 1.00 KDM4E (0.40) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL31022855 0.90 KDM4E (0.41) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL6409398 0.87 GABRR1 (0.46) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL6409392 0.87 GABRR1 (0.46) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL4746646 0.87 GABRR1 (0.46) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL15542332 0.86 KDM4E (0.42) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL813890 0.86 KDM4E (0.42) KDM4EMAPTKMT2AATMCYP2D6
SCHEMBL14898986 0.83
SCHEMBL4928801 0.83
SCHEMBL20487358 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US claimed
US-20230383245-A1 CULTURE MEDIUM COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-11-30 US disclosed
EP-2526921-B1 DENTAL RESTORATIVE MATERIAL KERR CORP (US) 2022-12-21 EP disclosed
US-20200095542-A1 CULTURE MEDIUM COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2020-03-26 US disclosed
US-10030483-B2 Carbon dioxide and hydrocarbon assisted enhanced oil recovery GENERAL ELECTRIC COMPANY (US) 2018-07-24 US disclosed
US-9642782-B2 Dental restorative material KERR CORPORATION (US) 2017-05-09 US disclosed
US-20170114269-A1 CARBON DIOXIDE AND HYDROCARBON ASSISTED ENHANCED OIL RECOVERY BAKER HUGHES, A GE COMPANY, LLC 2017-04-27 US disclosed
US-20170009201-A1 CULTURE MEDIUM COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-01-12 US disclosed
EP-3098300-A1 CULTURE MEDIUM COMPOSITION Nissan Chemical Industries, Ltd. (JP) 2016-11-30 EP disclosed
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2016-05-12 US disclosed
US-9237991-B2 Dental restorative material KERR CORPORATION (US) 2016-01-19 US disclosed
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION 2014-12-18 US disclosed
US-8822564-B2 Dental restorative material KERR CORPORATION (US) 2014-09-02 US disclosed
US-20120302662-A1 DENTAL RESTORATIVE MATERIAL KERR CORPORATION (US) 2012-11-29 US disclosed
US-6395803-B1 POLYMERIZABLE ACRYLIC MONOMER, FILLER AND AMIDE RHEOLOGICAL MODIFIER; SHRINKAGE INHIBITION, PHYSICAL PROPERTIES, WEAR RESISTANCE KERR CORPORATION 2002-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160128910-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 KDM4E 1954/4885MAPT 1270/4885KMT2A 1663/4885
US-20120302662-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 KDM4E 1954/4885MAPT 1270/4885KMT2A 1663/4885
US-20140371342-A1 DENTAL RESTORATIVE MATERIAL RPP30, RPL30, RPL6 KDM4E 1954/4885MAPT 1270/4885KMT2A 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.