Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409503 | 1.00 | MAPT (0.56) | MAPTNPSR1HTTCRHBPCRHR2 | |
| SCHEMBL6406629 | 0.82 | TSHR (0.55) | MAPTNPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL6403476 | 0.82 | TSHR (0.55) | MAPTNPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL6411991 | 0.81 | TSHR (0.56) | MAPTNPSR1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL6405347 | 0.77 | GAA (0.53) | MAPTNPSR1HTTALDH1A1TSHR | |
| 1,2,4-Triazole SCHEMBL6408146 | 0.73 | TSHR (0.45) | NPSR1TSHRLMNAGAA | |
| SCHEMBL6408031 | 0.72 | TSHR (0.65) | ALDH1A1TSHRLMNAGAAAVPR2 | |
| SCHEMBL6411005 | 0.70 | TSHR (0.54) | TSHRAVPR2AVPR1AL3MBTL1 | |
| SCHEMBL6405115 | 0.69 | TSHR (0.61) | NPSR1TSHRAVPR2AVPR1A | |
| SCHEMBL6402385 | 0.69 | ALDH1A1 (0.57) | NPSR1ALDH1A1TSHRLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | MAPT 2111/4885NPSR1 4536/4885HTT 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.