SCHEMBL640964

SCHEMBL640964

C=C(C)C(N)=O.CCC[N+](C)(C)CCCS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
DNM1 Q05193 3/20 0.36
BBOX1 O75936 1/20 0.35
ENPP2 Q13822 4/20 0.35
APP P05067 1/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
GRK2 P25098 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
EPHX2 P34913 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1913464 0.98 TDP1 (0.36) TDP1DNM1BBOX1ENPP2APP
SCHEMBL28060741 0.86
SCHEMBL1864397 0.85 DNM1 (0.48) DNM1BBOX1ENPP2APPMEN1
Acrylamide SCHEMBL3890433 0.84 DNM1 (0.36) DNM1BBOX1ENPP2APPMEN1
Water SCHEMBL1271206 0.83 DNM1 (0.46) DNM1BBOX1ENPP2APPMEN1
Hydrochloric Acid SCHEMBL27985007 0.82 DNM1 (0.47) TDP1DNM1BBOX1MEN1LMNA
SCHEMBL2099339 0.81 TDP1 (0.48) TDP1ENPP2APPLMNAPOLB
SCHEMBL2099691 0.80 TDP1 (0.46) TDP1APPEPHX2
SCHEMBL15305905 0.79 DNM1 (0.52) DNM1BBOX1APPKMT2AEPHX2
Hydrochloric Acid SCHEMBL15284900 0.79 DNM1 (0.59) TDP1DNM1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463767-B1 HIGH MOLECULAR WEIGHT CATIONIC AND ANIONIC POLYMERS COMPRISING ZWITTERIONIC MONOMERS NALCO CO (US) 2008-02-27 EP claimed
EP-1644198-B1 INK JET RECORDING MEDIUM CIBA SC HOLDING AG (CH) 2007-04-25 EP claimed
EP-1323753-A1 Self-adhesive cationic or amphoteric radical polymers and their use in cosmetic L'OREAL (FR) 2003-07-02 EP claimed
US-20220110863-A1 POLYMER COMPOSITE FOR CONTROLLED RELEASE OF AN AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION 2022-04-14 US disclosed
US-8119753-B2 Silicone hydrogels with amino surface groups BAUSCH & LOMB INCORPORATED (US) 2012-02-21 US disclosed
US-20090103045-A1 SILICONE HYDROGELS WITH AMINO SURFACE GROUPS SALIX PHARMACEUTICALS, INC. 2009-04-23 US disclosed
WO-2008108859-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED (US) 2008-09-12 WO disclosed
US-20080002146-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED 2008-01-03 US disclosed
US-20070132125-A1 Use of a super-cooled fluid in lens processing BAUSCH & LOMB INCORPORATED 2007-06-14 US disclosed
US-20070132121-A1 Method of cleaning molds using super-cooled fluids BAUSCH & LOMB INCORPORATED 2007-06-14 US disclosed
US-7147326-B2 Lens with colored portion and coated surface BAUSCH & LOMB INCORPORATED (US) 2006-12-12 US disclosed
EP-1179190-A1 SURFACE TREATMENT OF MEDICAL DEVICES WITH REACTIVE HYDROPHILIC POLYMERS BAUSCH & LOMB INCORPORATED (US) 2002-02-13 EP disclosed
WO-2001074932-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2001-10-11 WO disclosed
US-6200626-B1 OXIDATIVE PLASMA TREATMENT; PLASMA POLYMERIZATION; GRAFTING WITH AN ETHYLENICALLY UNSATURATED MONOMER BAUSCH & LOMB INCORPORATED 2001-03-13 US disclosed
WO-2000072052-A1 SURFACE TREATMENT OF MEDICAL DEVICES WITH REACTIVE HYDROPHILIC POLYMERS BAUSCH & LOMB INCORPORATED (US) 2000-11-30 WO disclosed
EP-0456390-B1 Copolymers with stain resistant properties ALLIED COLLOIDS LTD (GB) 1995-08-09 EP disclosed
US-5403821-A Water soluble copolymer containing a unsaturated acid and allyl ether compound NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1995-04-04 US disclosed
EP-0368563-B1 Drilling fluid additives NIPPON CATALYTIC CHEM IND (JP) 1994-02-16 EP disclosed
EP-0456390-A2 Copolymers with stain resistant properties Ciba Specialty Chemicals Water Treatments Limited (GB) 1991-11-13 EP disclosed
EP-0368563-A2 Drilling fluid additives NIPPON SHOKUBAI CO., LTD. (JP) 1990-05-16 EP disclosed