SCHEMBL640981

SCHEMBL640981

NCC(=O)C1COCC[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6579775 0.81
SCHEMBL4685862 0.78 HSD17B10 (0.30)
SCHEMBL2439644 0.78
SCHEMBL2228924 0.75
SCHEMBL7466110 0.74 PRKCA (0.36)
SCHEMBL2910375 0.69
SCHEMBL2429167 0.69 PPM1B (0.31)
SCHEMBL2909606 0.69
SCHEMBL4684128 0.69 HTT (0.36)
SCHEMBL4921798 0.69 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8847003-B2 Role of proteoglycans in drug dependence SANNA PIETRO P (US) 2014-09-30 US disclosed
US-8119854-B2 Role of proteoglycans in drug dependence Sanna, Pietro P. (US) 2012-02-21 US disclosed
US-20100199361-A1 Role of Proteoglycans in Drug Dependence Sanna, Pietro Paolo (US) 2010-08-05 US disclosed