Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | PRKCA | P17252 | 4/20 | 0.82 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.82 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.82 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.82 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.71 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.71 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL27636085 | 1.00 | ALDH1A1 (0.90) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| 1-Pentanol SCHEMBL28176665 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL22681323 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL13866569 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL13866563 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL27330834 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL19102029 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL13866570 | 0.95 | ALDH1A1 (0.87) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| Alcohol SCHEMBL1056469 | 0.95 | ALDH1A1 (0.93) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL23612380 | 0.95 | ALDH1A1 (1.00) | ALDH1A1LMNAPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230390216-A1 | BROMHEXINE FOR THE TREATMENT OF PAIN | KERN KAI UWE (DE) | 2023-12-07 | — | — | US | disclosed |
| EP-3638223-B1 | BROMHEXINE FOR THE TREATMENT OF PAIN | KERN KAI UWE (DE) | 2023-10-25 | — | — | EP | disclosed |
| US-11759439-B2 | Bromhexine for the treatment of pain | KERN KAI UWE (DE) | 2023-09-19 | — | — | US | disclosed |
| US-20200197330-A1 | BROMHEXINE FOR THE TREATMENT OF PAIN | KERN KAI UWE (DE) | 2020-06-25 | — | — | US | disclosed |
| EP-3638223-A1 | BROMHEXINE FOR THE TREATMENT OF PAIN | Kern, Kai-Uwe (DE) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018229119-A1 | BROMHEXINE FOR THE TREATMENT OF PAIN | KERN KAI UWE (DE) | 2018-12-20 | — | — | WO | disclosed |
| EP-3415143-A1 | BROMHEXINE FOR THE TREATMENT OF PAIN | Kern, Kai-Uwe (DE) | 2018-12-19 | — | — | EP | disclosed |
| CN-104363963-A | Topical dermal formulations and methods of personalized treatment of skin | FIBROCELL TECHNOLOGIES INC | 2015-02-18 | — | — | CN | disclosed |
| US-20050266058-A1 | Topical preparations containing ambroxol | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | US | disclosed |