Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036372 | 0.89 | HTR6 (0.53) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| SCHEMBL31333875 | 0.89 | HTR6 (0.53) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17630885 | 0.81 | HTR6 (0.59) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| SCHEMBL520900 | 0.81 | HTR6 (0.59) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| SCHEMBL4775022 | 0.80 | HTR6 (0.53) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| SCHEMBL519626 | 0.80 | HTR6 (0.50) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9958496 | 0.79 | HTR2C (0.57) | HTR6HTR2AADRA2APNMTHTR2C | |
| SCHEMBL519662 | 0.77 | HTR6 (0.53) | HTR6HTR2AADRA2APNMTALDH1A1 | |
| SCHEMBL5321082 | 0.77 | HTR6 (0.50) | HTR6HTR2AHTR2CSIGMAR1 | |
| SCHEMBL4789631 | 0.77 | HTR2C (0.56) | HTR6HTR2AADRA2APNMTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154020-A1 | 4-Aryl piperidines | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154020-A1 | 4-Aryl piperidines | MCHR1, MCHR2, MC1R | HTR6 54/4885HTR2A 48/4885ADRA2A 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.