Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405035 | 0.78 | MAPT (0.53) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10012011 | 0.76 | TSHR (0.52) | KMT2ASMN1; SMN2NPC1RAB9AVCP | |
| SCHEMBL254817 | 0.69 | MCL1 (0.61) | KMT2ASMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL6409749 | 0.68 | MEN1 (0.59) | KMT2ASMN1; SMN2RAB9AMAPTTSHR | |
| SCHEMBL6403796 | 0.68 | TSHR (0.57) | KMT2ASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL12905265 | 0.66 | MCL1 (0.57) | KMT2ASMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL14473813 | 0.66 | GAA (0.59) | KMT2ASMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL6404305 | 0.66 | ALDH1A1 (0.55) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10269942 | 0.65 | HRH3 (0.56) | KMT2ASMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL9306893 | 0.65 | MRGPRX4 (0.68) | KMT2ASMN1; SMN2NPC1RAB9AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885RXRA 2854/4885RXRB 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.