Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5249454 | 0.99 | HCRTR2 (0.41) | HCRTR2MAPTPKMPOLBSMN1; SMN2 | |
| SCHEMBL6414525 | 0.93 | HCRTR2 (0.41) | HCRTR2MAPTPKMPOLBOPRM1 | |
| Hydrochloric Acid SCHEMBL6414520 | 0.92 | HCRTR2 (0.41) | HCRTR2MAPTPKMPOLBOPRM1 | |
| SCHEMBL6409883 | 0.90 | HCRTR2 (0.39) | HCRTR2MAPTPOLBALDH1A1GAA | |
| SCHEMBL6409403 | 0.89 | MAPT (0.41) | HCRTR2MAPTPKMPOLBOPRD1 | |
| Hydrochloric Acid SCHEMBL6410061 | 0.89 | HCRTR2 (0.42) | HCRTR2MAPTPOLBOPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL6409401 | 0.89 | MAPT (0.40) | HCRTR2MAPTPKMPOLBOPRD1 | |
| Hydrochloric Acid SCHEMBL6409408 | 0.88 | HCRTR2 (0.41) | HCRTR2MAPTPOLBALDH1A1CCR5 | |
| SCHEMBL6410511 | 0.87 | CXCR3 (0.37) | OPRM1ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL6412131 | 0.87 | MAPT (0.44) | HCRTR2MAPTPKMPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA INC (CA) | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075326-A1 | Spiro compounds and methods for the modulation of chemokine receptor activity | CXCR1, CXCR4, CXCR2 | HCRTR2 247/4885MAPT 4525/4885PKM 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.