Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.59 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | RAF1 | P04049 | 2/20 | 0.59 |
| ▸ | LYN | P07948 | 2/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.59 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | SRC | P12931 | 3/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410468 | 0.85 | MAPK14 (0.76) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6807372 | 0.84 | MAPK14 (0.68) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6811097 | 0.84 | MAPK14 (0.66) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4081824 | 0.83 | MAPK14 (0.84) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL7534192 | 0.83 | MAPK14 (0.65) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6614260 | 0.82 | ABL1 (0.67) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6811116 | 0.82 | MAPK14 (0.70) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6808009 | 0.81 | MAPK14 (0.62) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6812272 | 0.81 | MAPK14 (0.68) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL5864520 | 0.81 | ABL1 (0.63) | MAPK14ABL1RAF1LYNMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050163726-A1 | Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-07-28 | — | — | US | disclosed |
| US-20040033222-A1 | Anticoagulant and fibrinolytic therapy uning p38 MAP kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050163726-A1 | Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors | CHRM3, CHRNB1, CHRM2 | MAPK14 83/4885ABL1 1495/4885RAF1 931/4885 |
| US-20040033222-A1 | Anticoagulant and fibrinolytic therapy uning p38 MAP kinase inhibitors | TFPI2, TFPI, PLG | MAPK14 30/4885ABL1 2261/4885RAF1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.