Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408279 | 0.92 | CYP3A4 (0.80) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6402486 | 0.92 | CYP3A4 (0.72) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6404838 | 0.91 | CYP3A4 (0.78) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6408014 | 0.91 | CYP3A4 (0.71) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6403463 | 0.88 | CYP3A4 (0.73) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6407146 | 0.88 | PTK2 (0.69) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL11511053 | 0.85 | MAPK1 (0.79) | CYP3A4CYP2C9PTK2MEN1KMT2A | |
| SCHEMBL6405467 | 0.83 | PTK2 (0.64) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6409127 | 0.82 | SMN1; SMN2 (0.80) | CYP3A4CYP2C9PTK2HDAC1HDAC2 | |
| SCHEMBL6404885 | 0.82 | TSHR (0.72) | CYP3A4CYP2C9MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | CYP3A4 25/4885CYP2C9 128/4885PTK2 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.