Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | METAP2 | P50579 | 2/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403463 | 0.91 | CYP3A4 (0.73) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL6406121 | 0.89 | SMN1; SMN2 (0.65) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL14426679 | 0.87 | SMN1; SMN2 (0.92) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL28375277 | 0.85 | SMN1; SMN2 (0.62) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL27952226 | 0.85 | MAPK1 (0.71) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL4206785 | 0.85 | RAB9A (0.75) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL31411197 | 0.84 | SMN1; SMN2 (0.63) | TSHRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL6405572 | 0.84 | HPGD (0.73) | TSHRALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6406205 | 0.83 | MEN1 (0.71) | TSHRALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL6251016 | 0.83 | ALDH1A1 (0.67) | TSHRALDH1A1HPGDNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | TSHR 3470/4885ALDH1A1 720/4885NPC1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.