Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.52 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.52 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311114 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL13311074 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL15006516 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL15040782 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL2039373 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL14852936 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL16847549 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL17366230 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL13347802 | 1.00 | LMNA (0.58) | LMNAALDH1A1POLBHSD17B10CYP2D6 | |
| SCHEMBL23457442 | 0.89 | LMNA (0.62) | LMNAALDH1A1POLBHSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562951-A2 | PORPHYRIN DERIVATIVES | Photobiotics Ltd. (GB) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046151-A2 | PORPHYRIN DERIVATIVES | PHOTOBIOTICS LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |