Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 13/20 | 0.49 |
| ▸ | CA2 | P00918 | 13/20 | 0.49 |
| ▸ | CA9 | Q16790 | 13/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4477596 | 0.86 | PTGS2 (0.57) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL4476914 | 0.82 | PTGS2 (0.57) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL4476916 | 0.79 | PTGS2 (0.46) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL2915550 | 0.77 | PTGS2 (0.57) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL2941675 | 0.72 | CA1 (0.51) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL2917637 | 0.72 | MEN1 (0.46) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL2910437 | 0.72 | RPA1 (0.70) | MEN1KMT2A | |
| SCHEMBL5529650 | 0.70 | RPA1 (0.57) | CA9MEN1KMT2A | |
| SCHEMBL5147886 | 0.70 | SMO (0.47) | MEN1KMT2A | |
| SCHEMBL5149016 | 0.70 | MALT1 (0.45) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |