Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413625 | 0.98 | STAT3 (0.38) | STAT3STAT1ADORA3KDM4EHSD17B10 | |
| SCHEMBL6414909 | 0.93 | ALDH1A1 (0.41) | STAT3STAT1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6418917 | 0.91 | GAA (0.44) | STAT3STAT1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6414089 | 0.89 | GAA (0.42) | STAT3STAT1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6417625 | 0.84 | ALDH1A1 (0.44) | ADORA3KDM4EHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6412535 | 0.83 | ABCG2 (0.45) | STAT3STAT1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6418943 | 0.82 | STAT3 (0.41) | STAT3STAT1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6413587 | 0.81 | ABCG2 (0.43) | STAT3STAT1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16673442 | 0.81 | STAT3 (0.44) | STAT3STAT1 | |
| SCHEMBL6420196 | 0.80 | STAT3 (0.40) | STAT3STAT1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071474-B1 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6479477-B1 | SUITABLE FOR USE IN MODULATING INTRA- AND EXTRACELLULAR PROCESSES IN WHICH SUPEROXIDE RADICALS, OR OTHER OXIDANTS SUCH AS HYDROGEN PEROXIDE OR PEROXYNITRITE, ARE A PARTICIPANT | DUKE UNIVERSITY | 2002-11-12 | — | — | US | disclosed |
| WO-1999055388-A9 | SUBSTITUTED PORPHYRINS | UNIV DUKE (US) | 2000-01-27 | — | — | WO | disclosed |