Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.46 |
| ▸ | HTR1A | P08908 | 16/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414402 | 0.94 | SLC6A4 (0.43) | SLC6A4HTR1ASLC6A2DRD2DRD3 | |
| SCHEMBL6418642 | 0.93 | SLC6A4 (0.44) | SLC6A4HTR1ADRD2DRD3KCNH2 | |
| SCHEMBL6410843 | 0.92 | HTR1A (0.54) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6416387 | 0.90 | HTR1A (0.61) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6417425 | 0.90 | HTR1A (0.43) | SLC6A4HTR1ACYP2D6TSHRMAPK1 | |
| SCHEMBL6412585 | 0.89 | HTR1A (0.51) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6417481 | 0.88 | HTR1A (0.52) | SLC6A4HTR1ACYP2D6 | |
| SCHEMBL6420145 | 0.85 | HTR1A (0.44) | SLC6A4HTR1ACYP2D6NOS3NOS1 | |
| SCHEMBL6412761 | 0.85 | SLC6A4 (0.40) | SLC6A4HTR1AHTTSLC6A2 | |
| SCHEMBL6412743 | 0.84 | HTR1A (0.59) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065140-A1 | Serotonine reuptake inhibitor | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1466901-A1 | SEROTONINE REUPTAKE INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065140-A1 | Serotonine reuptake inhibitor | HTR1A, SLC6A4, SLC6A2 | SLC6A4 2/4885HTR1A 1/4885CYP2D6 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.