Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25C | P30307 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917318 | 0.77 | CDC25C (1.00) | CDC25CMEN1KMT2ARECQLTHRB | |
| SCHEMBL2451270 | 0.72 | SIGMAR1 (0.68) | MEN1KMT2ARECQLCYP2D6CYP2C9 | |
| SCHEMBL2797012 | 0.72 | SIGMAR1 (0.68) | MEN1KMT2ARECQLCYP2D6CYP2C9 | |
| SCHEMBL2794528 | 0.72 | SIGMAR1 (0.68) | MEN1KMT2ARECQLCYP2D6CYP2C9 | |
| SCHEMBL1917474 | 0.69 | CDC25C (1.00) | CDC25CMEN1KMT2ARECQLTHRB | |
| SCHEMBL31443250 | 0.67 | SLC6A4 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL4856667 | 0.67 | CYP2D6 (0.51) | MEN1KMT2ARECQLTHRBCYP2D6 | |
| Hydrochloric Acid SCHEMBL11431779 | 0.67 | MAPT (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL11431784 | 0.67 | MAPT (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL9800427 | 0.66 | GAA (0.73) | KMT2APOLBMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |
| EP-1370255-A2 | CDC25 PHOSPHATASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002009686-A2 | CDC25 PHOSPHATASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2002-02-07 | — | — | WO | disclosed |