⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823725 | 0.69 | — | — | |
| SCHEMBL16792522 | 0.65 | — | — | |
| SCHEMBL2899353 | 0.61 | — | — | |
| SCHEMBL60584 | 0.59 | — | — | |
| SCHEMBL6443151 | 0.56 | — | — | |
| SCHEMBL6443148 | 0.56 | — | — | |
| SCHEMBL16792521 | 0.54 | — | — | |
| SCHEMBL18393762 | 0.54 | — | — | |
| SCHEMBL23159 | 0.52 | — | — | |
| SCHEMBL3855766 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050053552-A1 | Phase shift colloids as ultrasound contrast agents | QUAY STEVEN C (US) | 2005-03-10 | — | — | US | disclosed |
| US-6569404-B1 | Aqueous colloidal suspension, dispersed phase is gas microbubbles of perfluoropropane, perfluorobutane, perfluoropentane, perfluorohexane or sulfur hexafluoride; fluorinated amphiphile for stabilizing microbubbles | AMERSHAM HEALTH A/S (NO) | 2003-05-27 | — | — | US | disclosed |
| US-6245319-B1 | Colloidal dispersions of perfluoropentane | SONUS PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| EP-0680341-B1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMA INC (US) | 2001-05-09 | — | — | EP | disclosed |
| EP-1038535-A2 | Use of selected perfluorocarbons for the preparation of diagnostic ultrasound contrast agents | SONUS PHARMACEUTICALS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| US-5876696-A | Composition comprising a fluorine containing surfactant and perfluoropentane for ultrasound | SONUS PHARMACEUTICALS, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5558853-A | WATER IMMISCIBLE FLUORINE COMPOUND | SONUS PHARMACEUTICALS (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0030663-B1 | LAYER-MODIFIED PARTICULATED FLUOROPOLYMERS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-12 | — | — | EP | disclosed |
| US-4391940-A | POLYMERS/SHELL-CORE/ | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| EP-0030663-A2 | Layer-modified particulated fluoropolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-24 | — | — | EP | disclosed |