Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 16/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620642 | 0.92 | GRIA2 (0.73) | GRIA2 | |
| SCHEMBL5351047 | 0.85 | GRIA2 (0.67) | GRIA2 | |
| SCHEMBL5484687 | 0.85 | GRIA2 (0.58) | GRIA2 | |
| SCHEMBL5620490 | 0.84 | GRIA2 (0.71) | GRIA2 | |
| SCHEMBL5621206 | 0.83 | GRIA2 (0.60) | GRIA2 | |
| SCHEMBL5619678 | 0.81 | GRIA2 (0.73) | GRIA2 | |
| SCHEMBL5621569 | 0.81 | GRIA2 (0.57) | GRIA2 | |
| SCHEMBL5185245 | 0.81 | GRIA2 (0.84) | GRIA2 | |
| SCHEMBL6505317 | 0.81 | GRIA2 (0.72) | GRIA2 | |
| SCHEMBL5184614 | 0.80 | GRIA2 (0.70) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065146-A1 | Novel benzothiazine and benzothiadiazine derivatives, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-03-24 | — | — | US | disclosed |
| EP-1472219-A1 | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003053978-A1 | NOVEL BENZOTHIAZINE AND BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065146-A1 | Novel benzothiazine and benzothiadiazine derivatives, method for preparing same and pharmaceutical compositions containing same | NR5A2, NR4A3, CBR3 | GRIA2 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.